ATP5S blocking peptide

ATP5S Blocking Peptide (N-term)

• Gene Names: ATP5S; FB; ATPW; HSU79253
• Synonyms: ATP5S; ATP5S Blocking Peptide (N-term); ATP synthase subunit s; mitochondrial; ATP synthase-coupling factor B; FB; Mitochondrial ATP synthase regulatory component factor B; ATPW; ATP5S blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 51-64 of HUMAN ATP5S
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 215

• Cellular Location: Mitochondrion. Mitochondrion inner membrane
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ATP5S blocking peptide

Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 51558774
• NCBI GeneID: 27109
• NCBI Accession #: NP_001003803.1
• NCBI GenBank Nucleotide #: NM_001003803.2
• UniProt Accession #: Q99766; Q8WWX3; Q96F77; A8K1U3; D9N156
• Molecular Weight: 14,667 Da
• NCBI Official Full Name: ATP synthase subunit s, mitochondrial isoform a
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
• NCBI Official Symbol: ATP5S
• NCBI Official Synonym Symbols: FB; ATPW; HSU79253
• NCBI Protein Information: ATP synthase subunit s, mitochondrial
• UniProt Protein Name: ATP synthase subunit s, mitochondrial
• Protein Family: ATP synthase
• UniProt Gene Name: ATP5S
• UniProt Synonym Gene Names: ATPW; FB
• UniProt Entry Name: ATP5S_HUMAN

NCBI Description

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP5S: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway. Belongs to the ATP synthase subunit s family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 14q21.3

Cellular Component: mitochondrial inner membrane

Biological Process: ATP biosynthetic process; mitochondrial ATP synthesis coupled proton transport