ARHGEF5 blocking peptide
ARHGEF5 Peptide
Gene Names
ARHGEF5; P60; TIM; GEF5; TIM1
Applications
Blocking
Purity
Synthetic peptide ARHGEF5. (Note: the amino acid sequence is proprietary).The purity is >98%.
Synonyms
ARHGEF5; ARHGEF5 Peptide; Rho guanine nucleotide exchange factor 5; Ephexin-3; Ephexin 3; Ephexin3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM; TIM; ARHGEF5 blocking peptide
Specificity
This peptide can be used with studies using MBS3006055 ARHGEF5 pAb.
Purity/Purification
Synthetic peptide ARHGEF5. (Note: the amino acid sequence is proprietary).
The purity is >98%.
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
1597
Applicable Applications for ARHGEF5 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for ARHGEF5 blocking peptide
Rho GTPases, which play fundamental roles in numerous cellular processes, are initiated by external stimuli that signal though G-protein coupled receptors. ARHGEF5 (Rho guanine nucleotide exchange factor (GEF) 5), also known as P60 or transforming immortalized mammary oncogene (TIM), is a 1597 amino acid cytoplasmic protein. ARHGEF5 is believed to form a complex with G proteins and be involved in the initiation of Rho-dependent signals. It has also been suggested that ARHGEF5 may be involved in the organization of the cytoskeleton. ARHGEF5 contains one PH domain, one DH domain and one SH3 domain. Existing as two isoforms produced by alternative splicing, ARHGEF5 is mainly expressed in pancreas, liver, kidney, placenta and lung.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
rho guanine nucleotide exchange factor 5
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor 5
NCBI Official Symbol
ARHGEF5
NCBI Official Synonym Symbols
P60; TIM; GEF5; TIM1
NCBI Protein Information
rho guanine nucleotide exchange factor 5
UniProt Protein Name
Rho guanine nucleotide exchange factor 5
Protein Family
UniProt Gene Name
ARHGEF5
UniProt Synonym Gene Names
TIM
UniProt Entry Name
ARHG5_HUMAN
NCBI Description
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
Uniprot Description
ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; Oncoprotein; Motility/polarity/chemotaxis; GEFs, Rac/Rho
Chromosomal Location of Human Ortholog: 7q35
Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTP binding
Biological Process: myeloid dendritic cell chemotaxis; actin cytoskeleton organization and biogenesis
Research Articles on ARHGEF5
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Product Notes
The ARHGEF5 arhgef5 (Catalog #AAA3006056) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ARHGEF5 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the ARHGEF5 arhgef5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGEF5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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