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ALDH3B1 blocking peptide

ALDH3B1 Antibody (Center) Blocking Peptide

Gene Names
ALDH3B1; ALDH4; ALDH7
Synonyms
ALDH3B1; ALDH3B1 Antibody (Center) Blocking Peptide; Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7; ALDH7; ALDH3B1 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human ALDH3B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
468
Cellular Location
Cell membrane; Lipid-anchor. Note: Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm
Tissue Location
Highest expression in kidney and lung.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ALDH3B1 blocking peptide
Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
221
UniProt Accession #
Molecular Weight
47,683 Da
NCBI Official Full Name
Aldehyde dehydrogenase family 3 member B1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family member B1
NCBI Official Symbol
ALDH3B1
NCBI Official Synonym Symbols
ALDH4; ALDH7
NCBI Protein Information
aldehyde dehydrogenase family 3 member B1
UniProt Protein Name
Aldehyde dehydrogenase family 3 member B1
UniProt Gene Name
ALDH3B1
UniProt Synonym Gene Names
ALDH7
UniProt Entry Name
AL3B1_HUMAN

NCBI Description

This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Amino Acid Metabolism - histidine; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.2.1.5; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; plasma membrane; vesicle

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; protein binding

Biological Process: alcohol metabolic process; aldehyde catabolic process; lipid metabolic process; sphingolipid biosynthetic process

Research Articles on ALDH3B1

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Product Notes

The ALDH3B1 aldh3b1 (Catalog #AAA9227801) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ALDH3B1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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