ACAT2 blocking peptide

ACAT2 Blocking Peptide

Cat. Num. AAA9621511

• Gene Names: SOAT2; ACAT2; ARGP2; ACACT2
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: ACAT2; ACAT2 Blocking Peptide; ACACT2; ACAT 2; Acyl Co A: cholesterol acyltransferase 2; Acyl CoA:cholesterol acyltransferase 2; acyl coenzyme A cholestrol acyltransferase 2; Acyl coenzyme A:cholesterol acyltransferase 2; ARGP2; Cholesterol acyltransferase 2; Sterol O acyl transferase 2; ACAT2 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for ACAT2 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ACAT2 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 68563320
• NCBI GeneID: 8435
• UniProt Accession #: O75908; Q4VB99; Q4VBA1; Q96TD4; Q9UNR2; F5H7W4; I6L9H9
• Molecular Weight: 57,614 Da
• NCBI Official Full Name: SOAT2 protein
• NCBI Official Synonym Full Names: sterol O-acyltransferase 2
• NCBI Official Symbol: SOAT2
• NCBI Official Synonym Symbols: ACAT2; ARGP2; ACACT2
• NCBI Protein Information: sterol O-acyltransferase 2
• UniProt Protein Name: Sterol O-acyltransferase 2
• Protein Family: Acetyl-CoA acetyltransferase
• UniProt Gene Name: SOAT2
• UniProt Synonym Gene Names: ACACT2; ACAT2; ACAT-2

NCBI Description

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.