Structure
Tetrandrine Biochemical
Tetrandrine
Purity
>98% (HPLC)
Synonyms
Tetrandrine; NSC 77037; Fanchinine; Tetrandrine biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 1mg/mL (1.61mM)
Ethanol: 2mg/mL (3.21mM), warmed
Water: <1mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)
Ethanol: 2mg/mL (3.21mM), warmed
Water: <1mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Calcium Channel
Receptor
CalciumChannel
Chemical Name
d-tetrandrine
SMILES
COC1=C(C2=C(C=C1OC)CCN(C)[C@]2(C3)[H])OC4=CC5=C(C=C4OC)CCN(C)[C@]5(CC6=CC=C(OC7=CC3=CC=C7OC)C=C6)[H]
Molecular Formula
C38H42N2O6
CAS Number
518-34-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Tetrandrine biochemical
Tetrandrine (NSC 77037; Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20uM for L-type and T-type calcium channels, respectively) and induces apoptosis; produces anti-inflammatory, immunomodulating, anti-proliferative, and free radical scavenging effects; has also been shown to increase glucose utilization by enhancing hepatocyte glycogen synthesis; a potent cell autophagy agonist. Lung Cancer Phase 3 Clinical
Product Categories/Family for Tetrandrine biochemical
References
1. Xie QM, et al. Acta Pharmacol Sin. 2002 Dec; 23 (12):1107-13.
2. Yang Z, et al. Sci Rep. 2016 Jul 26; 6:30263.
3. Wang H, et al. Cell Biosci. 2015 Jan 14; 5:4.
2. Yang Z, et al. Sci Rep. 2016 Jul 26; 6:30263.
3. Wang H, et al. Cell Biosci. 2015 Jan 14; 5:4.
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Product Notes
The Tetrandrine (Catalog #AAA3604811) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tetrandrine, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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