Structure
SNAP-37889 Biochemical
SNAP-37889
Purity
>98% (HPLC)
Synonyms
SNAP-37889; HT-2157; HT2157; HT 2157; SNAP37889; SNAP 37889; SNAP-37889 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=29mg/mL
Target
Galanin Receptor
Receptor
Galanin Receptor
Chemical Name
2H-Indol-2-one, 1, 3-dihydro-1-phenyl-3-[[3-(trifluoromethyl)phenyl]imino]
SMILES
O=C1N(C2=CC=CC=C2)C3=C(C=CC=C3)/C1=N/C4=CC=CC(C(F)(F)F)=C4
Molecular Formula
C21H13F3N2O
CAS Number
303149-14-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SNAP-37889 biochemical
A potent, selective galanin-3 receptor (Gal3) antagonist with Ki of 17.44nM, displays highly selective for Gal3 over the Gal1 and Gal2 subtypes (both Ki >10uM); attenuates stress-induced hyperthermia in mice, partially antagonizes the galanin-evoked reduction in hippocampal serotonin, exhibits anxiolytic- and antidepressant-like profiles in vivo. Depression Phase 2 Clinical
Product Categories/Family for SNAP-37889 biochemical
References
1. Swanson CJ, et al. Proc Natl Acad Sci U S A. 2005 Nov 29; 102 (48):17489-94.
2. Ash BL, et al. Regul Pept. 2011 Jan 17; 166 (1-3):59-67.
3. Koller A, et al. Neuropeptides. 2016 Apr; 56:83-8.
4. Scheller KJ, et al. Neuropharmacology. 2017 May 15; 118:1-12.
2. Ash BL, et al. Regul Pept. 2011 Jan 17; 166 (1-3):59-67.
3. Koller A, et al. Neuropeptides. 2016 Apr; 56:83-8.
4. Scheller KJ, et al. Neuropharmacology. 2017 May 15; 118:1-12.
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Product Notes
The SNAP-37889 (Catalog #AAA3603953) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SNAP-37889, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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