Structure
SF1670 biochemical
SF1670
Purity
>=98%
Synonyms
SF1670; N-?(9; ?10-?dihydro-?9; ?10-?dioxo-?2-?phenanthrenyl)-?2; ?2-?dimethyl-?propanamide; SF1670 biochemical
Purity/Purification
>=98%
Form/Format
Appearance: Light pink to dark purple solid
CAS Number
345630-40-2
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Y
PubChem CID
9926586
Solubility/Reconstitution Instructions
DMSO (~ 10 mg/ml)
SMILES
CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O
InChi
InChI=1S/C19H17NO3/c1-19(2,3)18(23)20-11-8-9-13-12-6-4-5-7-14(12)16(21)17(22)15(13)10-11/h4-10H,1-3H3,(H,20,23)
InChi Key
VZQDDSYKVYARDW-UHFFFAOYSA-N
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Shelf Life: 36 months
Structure
Structure
Related Product Information for SF1670 biochemical
Background: SF1670 is a selective PTEN (phosphatase and tensin homolog) inhibitor (IC?? = 2 uM). It specifically binds to the active site of PTEN. At nanomolar concentrations it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. Pretreatment with SF1670 has been used to enhance PIP3 signaling in transplanted neutrophils, augmenting their function at sites of infection in neutropenic recipient mice.
Product Categories/Family for SF1670 biochemical
Similar Products
Product Notes
The SF1670 (Catalog #AAA843160) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SF1670, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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