Structure
PRT4165 biochemical
PRT4165
Purity
>=98% by HPLC
Synonyms
PRT4165; 2- (3-Pyridinylmethylene)-1H-Indene-1; 3 (2H)-dione; NSC600157; PRT4165 biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Yellow solid
Salt Form
No
Molecular Formula
C15H19NO2
CAS Number
31083-55-3
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
C1=CC=C2C(=C1)C(=O)C(=CC3=CN=CC=C3)C2=O
InChi
InChI=1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H
InChi Key
OMHZFEWYVFWVLI-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Protect from air and light.
Structure
Structure
Related Product Information for PRT4165 biochemical
PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1; RNF2; and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX. In addition; it prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2alpha (Top2alpha).
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Product Notes
The PRT4165 (Catalog #AAA846201) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PRT4165, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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