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Structure

Plumbagin Biochemical

Plumbagin

Purity
>=98%
Synonyms
Plumbagin; 5-Hydroxy-2-methyl-1; 4-naphthalened-ione; Plumbagin biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98%
Form/Format
Appearance: Orange red solid
CAS Number
481-42-5
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00001682
PubChem CID
10205
Solubility/Reconstitution Instructions
DMSO (~20 mg/ml) or EtOH (~10 mg/ml)
SMILES
CC1=CC(=O)C2=C(C1=O)C=CC=C2O
InChi
InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3
InChi Key
VCMMXZQDRFWYSE-UHFFFAOYSA-N
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months

Structure

Structure
Related Product Information for Plumbagin biochemical
Background: A quinonoid constituent isolated from the root of Plumbago zeylanica. Displays anticarcinogenic, antiatherosclerotic, and antimicrobial effects as well as anticancer and antiproliferation properties in a variety of cell lines and animal models. Induces G2/M and autophagy in breast cancer cells by inhibiting Akt/mTOR pathway. Also potently inhibits histone acetyltransferase (HAT) activity in vivo. Plumbagin specifically inhibits p300-mediated acetylation of p53 but not the acetylation by p300/CREB-binding protein associated factor, PCAF, in vivo.

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Product Notes

The Plumbagin (Catalog #AAA843121) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Plumbagin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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