Structure
Nimbolide Biochemical
Nimbolide
Purity
>=98% by TLC
Synonyms
Nimbolide; (4alpha; 5alpha; 6alpha; 7alpha; 15beta; 17alpha)-7; 15:21; 23-Diepoxy-6-hydroxy-4; 8-dimethyl-1-oxo-18; 24-dinor-11; 12-secochola-2; 13; 20; 22-tetraene-4; 11-dicarboxylic alphacid gamma-lactone Methyl Ester; CCRIS 5723; NSC-309909; Nimbolide biochemical
Purity/Purification
>=98% by TLC
Form/Format
Appearance: White to off-white solid
CAS Number
25990-37-8
Structure Available
Yes
Salt Form
No
Cell-Permeable
Yes
MDL Number
MFCD01735386
PubChem CID
100017
Molecular Formula
C27H30O7
Appearance
Off-white solid
Solubility/Reconstitution Instructions
DMSO (~50 mM) or Ethanol (~ 8 mM)
SMILES
CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C
InChi
InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3
InChi Key
JZIQWNPPBKFOPT-UHFFFAOYSA-N
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Shelf Life: 36 months
Structure
Structure
Related Product Information for Nimbolide biochemical
Background: A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis through three distinct mechanisms: reactive oxygen species and ERK-mediated up-regulation of DR5 and DR4, downregulation of cell survival proteins, and up-regulation of pro-apoptotic proteins p53 and Bax.
Product Categories/Family for Nimbolide biochemical
Similar Products
Product Notes
The Nimbolide (Catalog #AAA842213) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Nimbolide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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