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Structure

LJI308 Biochemical

LJI308

Purity
>98% (HPLC)
Synonyms
LJI308; LJI-308; LJI 308; NVP-LJI308; NVP-LJI-308; LJI308 biochemical
Ordering
For Research Use Only!
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=32mg/mL (86.87mM)
Target
PDE
Receptor
RSK1; RSK2; RSK3
Chemical Name
2, 6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]-phenol
SMILES
Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1
Molecular Formula
C21H18F2N2O2
CAS Number
1627709-94-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for LJI308 biochemical
LJI308 is a RSK inhibitor. LJI308 overcomes chemoresistance by eliminating cancer stem cells. LJI308 targets the CSC population and repress TNBC growth and dissemination. LJI308 specifically targeted transformed cells as it had little effect on the non-tumorigenic parental HMECs. Targeting RSK using specific and potent inhibitors, such as LJI308, delivers the promise of inhibiting the growth of TNBC.
Product Categories/Family for LJI308 biochemical
References
1.Aronchik I, Appleton B A, Basham S E, et al. Molecular Cancer Research, 2014, 12 (5): 803-812.

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Product Notes

The LJI308 (Catalog #AAA3607339) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LJI308, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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