Structure
Deferasirox Biochemical
Deferasirox
Purity
>=98%
Synonyms
Deferasirox; ICL670A; 4-[3; 5-bis (2-hydroxyphenyl)-1H-1; 2; 4-triazol-1-yl]-benzoic acid; Deferasirox biochemical
Purity/Purification
>=98%
Form/Format
White to pale yellow or purple powder
Solubility
>20 mg/ml in DMSO
Molecular Formula
C??H??N?O?
CAS Number
201530-41-8
MDL Number
MFCD09951804
PubChem CID
214348
SMILES
C1=CC=C (C (=C1)C2=NN (C (=N2)C3=CC=CC=C3O)C4=CC=C (C=C4)C (=O)O)O
InChi
InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15 (17)19-22-20 (16-6-2-4-8-18 (16)26)24 (23-19)14-11-9-13 (10-12-14)21 (27)28/h1-12,25-26H, (H,27,28)
InChi Key
BOFQWVMAQOTZIW-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for Deferasirox biochemical
Deferasirox is an orally bioavailable tridentate iron chelator. It is selective for iron (Fe (III) ) over Cu (II), Zn (II), Mg (II), and Ca (II) but does bind to Al (III). Deferasirox decreases iron levels in iron-loaded rat heart cells in vitro by 45.8 and 55.6% compared to control levels when used at concentrations of 160 and 320 uM, respectively. Deferasirox also inhibits proliferation of SAS human oral squamous carcinoma cells (EC50 = 21 uM), decreases cyclin D1 protein levels, and increases protein levels of N-Myc downregulated gene 1 (NDRG1) and NDRG3.
Product Categories/Family for Deferasirox biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/214348
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Product Notes
The Deferasirox (Catalog #AAA848917) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Deferasirox, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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