Structure
CLOZAPINE N-OXIDE Biochemical
CLOZAPINE N-OXIDE
Purity
>98% (HPLC)
Synonyms
CLOZAPINE N-OXIDE; Clozapine N-oxide; CLOZAPINE N-OXIDE biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=100mg/mL (291.70mM)
Methanol: >=28.6mg/mL (83.43mM)
H2O: 1mg/mL (2.92mM)
Methanol: >=28.6mg/mL (83.43mM)
H2O: 1mg/mL (2.92mM)
Target
Other Targets
Receptor
Others
Chemical Name
3-Chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1, 4]benzodiazepine
SMILES
Clc1ccc2Nc4ccccc4C(=Nc2c1)N3CC[N+]([O-])(C)CC3
Molecular Formula
C18H19ClN4O
CAS Number
34233-69-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CLOZAPINE N-OXIDE biochemical
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo.
Product Categories/Family for CLOZAPINE N-OXIDE biochemical
References
1. Dain, J.G., et al. Biotransformation of clozapine in humans. Drug Metabolism and Disposition 25 (5), 603-609 (1997).
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Product Notes
The CLOZAPINE N-OXIDE (Catalog #AAA3608441) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CLOZAPINE N-OXIDE, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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