Structure
AZD-0837 Biochemical
AZD-0837
Purity
>98% (HPLC)
Synonyms
AZD-0837; AZD0837; Atecegatran metoxil; AZD-0837 biochemical
Purity/Purification
>98% (HPLC)
Target
Thrombin
Receptor
Thrombin
Chemical Name
(S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide
SMILES
O=C([C@H]1N(C([C@@H](C2=CC(OC(F)F)=CC(Cl)=C2)O)=O)CC1)NCC3=CC=C(C(NOC)=N)C=C3
Molecular Formula
C22H23ClF2N4O5
CAS Number
433937-93-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AZD-0837 biochemical
AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor, has been investigated in phase II studies for prevention of stroke and systemic embolic events in patients with atrial fibrillation (AF).Thrombosis Phase 2 Discontinued
Product Categories/Family for AZD-0837 biochemical
References
1. Schutzer KM, et al. Eur J Clin Pharmacol. 2010 Sep; 66 (9):903-10.
2. Lip GY, et al. Thromb Res. 2011 Feb; 127 (2):91-9.
3. Matsson EM, et al. Mol Pharm. 2013 Nov 4; 10 (11):4252-62.
4. Deinum J, et al. Thromb Haemost. 2009 Jun; 101 (6):1051-9.
2. Lip GY, et al. Thromb Res. 2011 Feb; 127 (2):91-9.
3. Matsson EM, et al. Mol Pharm. 2013 Nov 4; 10 (11):4252-62.
4. Deinum J, et al. Thromb Haemost. 2009 Jun; 101 (6):1051-9.
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Product Notes
The AZD-0837 (Catalog #AAA3604476) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AZD-0837, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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