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Structure

AMMC iodide Biochemical

AMMC iodide

Purity
>=98% by NMR
Synonyms
AMMC iodide; 3-[2-(N; N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin iodide; AMMC iodide biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by NMR
Form/Format
Appearance: Off-white solid
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
No
MDL Number
MFCD13184322
PubChem CID
15487105
Solubility/Reconstitution Instructions
Acetonitrile
SMILES
CC[N+](C)(CC)CCC1=C(C2=C(C=C(C=C2)OC)OC1=O)C.[I-]
InChi
InChI=1S/C18H26NO3.HI/c1-6-19(4,7-2)11-10-16-13(3)15-9-8-14(21-5)12-17(15)22-18(16)20;/h8-9,12H,6-7,10-11H2,1-5H3;1H/q+1;/p-1
InChi Key
OAQIUABCTPFMOC-UHFFFAOYSA-M
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months

Structure

Structure
Related Product Information for AMMC iodide biochemical
Background: AMMC iodide is a useful substrate for the human cytochrome P450 CYP2D6 isozyme. It is demethylated to the fluorescent product 3-[2-(N,N-diethyl-N-methyl ammonium)ethyl]-7-hydroxy-4-methylcoumarin (AMHC). After the AMMC is hydrolyzed, the pH is increased by addition of base for optimal fluorescence detection. AMMC has been used with human liver microsomes to determine CYP2D6 activity and inhibition.

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Product Notes

The AMMC iodide (Catalog #AAA842538) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AMMC iodide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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