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Structure

AEM1 Biochemical

AEM1

Purity
>=98% by HPLC
Synonyms
AEM1; N- (1; 3-Benzodioxol-5-ylmethyl)-5- (4-fluorophenyl)-thieno[2; 3-d]pyrimidin-4-amine; AEM1 biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by HPLC
Form/Format
Crystalline solid
Solubility
~20 mg/ml in DMSO
Molecular Formula
C??H??FN?O?S
CAS Number
1030123-90-0
PubChem CID
9196193
SMILES
C1OC2=C (O1)C=C (C=C2)CNC3=C4C (=CSC4=NC=N3)C5=CC=C (C=C5)F
InChi
InChI=1S/C20H14FN3O2S/c21-14-4-2-13 (3-5-14)15-9-27-20-18 (15)19 (23-10-24-20)22-8-12-1-6-16-17 (7-12)26-11-25-16/h1-7,9-10H,8,11H2, (H,22,23,24)
InChi Key
QGYLTGSHWIGJJD-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months

Structure

Structure
Related Product Information for AEM1 biochemical
AEM1 is an inhibitor of Nrf2-induced gene transcription at the antioxidant response element in cells at 1 to 10 uM. It sensitizes lung carcinoma A549 cells to chemotherapeutic agents and inhibits the growth of A549 cells in vitro and in vivo in animals.
References
https://pubchem.ncbi.nlm.nih.gov/compound/9196193

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Product Notes

The AEM1 (Catalog #AAA848882) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AEM1, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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