Structure
2,4-Pyridinedicarboxylic Acid Biochemical
2,4-Pyridinedicarboxylic Acid
Purity
>=98%
Synonyms
2; 4-Pyridinedicarboxylic Acid; 4-Lutidinic acid; 4-Dicarboxypyridine; 4-carboxypicolinic acid; histone lysine demethylase inhibitor; Lutidinic acid; 4-Pyridinedicarboxylic Acid biochemical
Purity/Purification
>=98%
Form/Format
Crystalline solid
Solubility
~1.4 mg/ml in DMSO
Molecular Formula
C?H?NO?
CAS Number
499-80-9
MDL Number
MFCD00006296
PubChem CID
10365
SMILES
C1=CN=C (C=C1C (=O)O)C (=O)O
InChi
InChI=1S/C7H5NO4/c9-6 (10)4-1-2-8-5 (3-4)7 (11)12/h1-3H, (H,9,10)(H,11,12)
InChi Key
MJIVRKPEXXHNJT-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for 2,4-Pyridinedicarboxylic Acid biochemical
2,4-Pyridinedicarboxylic Acid is an inhibitor of histone lysine demethylases and 2-oxoglutarate oxygenases. It structurally mimics 2-oxoglutarate (2-OG) and chelates zinc, thus inhibiting a range of enzymes. As a 2-OG mimic it also inhibits prolyl, collagen and lysyl hydroxylases. It modulates hypoxia-inducible factor turnover, collagen synthesis and plant cell wall formation. It also inhibits zinc-dependent enzymes, like metallo-beta-lactamase. It inhibits several Jumonji domain-containing lysine demethylases such as JMJD2A (KDM4A) and KDM4C. It reduced neointimal hyperplasia and inflammation in the carotid arteries of Diabetic Rats.
Product Categories/Family for 2,4-Pyridinedicarboxylic Acid biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/10365
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Product Notes
The 2,4-Pyridinedicarboxylic Acid (Catalog #AAA848944) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "2,4-Pyridinedicarboxylic Acid, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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