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BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2 Recombinant Protein | BHMT2 recombinant protein

Human BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2 Recombinant Protein

Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2; Human BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2 Recombinant Protein; S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase; Betaine--homocysteine S-methyltransferase 2; BHMT2 recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
363
Applicable Applications for BHMT2 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Homotetramer (By similarity). May interact with PRNP.
Entry Function
Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
S-methylmethionine--homocysteine S-methyltransferase BHMT2 isoform 1
NCBI Official Synonym Full Names
betaine--homocysteine S-methyltransferase 2
NCBI Official Symbol
BHMT2
NCBI Protein Information
S-methylmethionine--homocysteine S-methyltransferase BHMT2
UniProt Protein Name
S-methylmethionine--homocysteine S-methyltransferase BHMT2
UniProt Gene Name
BHMT2
UniProt Synonym Gene Names
SMM-hcy methyltransferase

NCBI Description

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Uniprot Description

Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.

Research Articles on BHMT2

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Product Notes

The BHMT2 bhmt2 (Catalog #AAA2902814) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the BHMT2 bhmt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BHMT2 / S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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