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SDS-Page

Bestrophin 2 (BEST2) Recombinant Protein | BEST2 recombinant protein

Recombinant Bestrophin 2 (BEST2)

Gene Names
BEST2; VMD2L1
Applications
SDS-Page, Western Blot
Purity
> 95%
Synonyms
Bestrophin 2 (BEST2); Recombinant Bestrophin 2 (BEST2); VMD2L1; Vitelliform Macular Dystrophy 2-Like 1; BEST2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95%
Form/Format
Freeze-dried powder
Sequence Length
509
Applicable Applications for BEST2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Fragment
Leu320~Ala509
Tag
N-terminal His-tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Source Note
Prokaryotic expression
Organism Species
Human
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Isoelectric Point
4.1
Subcellular Location
Cell Membrane. Multi-pass Membrane Protein.
Usage
Reconstitute in PBS or others.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

SDS-Page
Product Categories/Family for BEST2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23.6kDa
NCBI Official Full Name
bestrophin-2
NCBI Official Synonym Full Names
bestrophin 2
NCBI Official Symbol
BEST2
NCBI Official Synonym Symbols
VMD2L1
NCBI Protein Information
bestrophin-2
UniProt Protein Name
Bestrophin-2
Protein Family
UniProt Gene Name
BEST2
UniProt Synonym Gene Names
VMD2L1

NCBI Description

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]

Uniprot Description

BEST2: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 19p13.13

Cellular Component: cilium; integral to plasma membrane

Molecular Function: chloride channel activity

Biological Process: membrane depolarization; sensory perception of smell

Research Articles on BEST2

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Product Notes

The BEST2 best2 (Catalog #AAA2086893) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bestrophin 2 (BEST2) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the BEST2 best2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bestrophin 2 (BEST2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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