Typical Testing Data/Standard Curve (for reference only)
Mouse B-cell lymphoma/leukemia 10 ELISA Kit | Bcl10 elisa kit
Mouse B-cell lymphoma/leukemia 10 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
Bcl-10: a ubiquitous pro-apoptotic protein that promotes pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Self-associates via CARD-CARD interactions; forms a tight complex with MALT1. Interacts with other CARD-proteins such as CARD9, CARD10, CARD11 and CARD14. Binds caspase-9 with its C-terminal domain. Interacts with TRAF2 and BIRC2/c-IAP2. Defects in BCL10 are involved in various types of cancer.
Protein type: Apoptosis; Transcription, coactivator/corepressor; Tumor suppressor
Cellular Component: cytoplasm; cytoplasmic microtubule; cytosol; immunological synapse; lipid raft; lipopolysaccharide receptor complex; lysosome; membrane; nucleus; perinuclear region of cytoplasm; protein complex; T cell receptor complex
Molecular Function: caspase activator activity; enzyme binding; kinase activator activity; kinase binding; NF-kappaB binding; protease binding; protein binding; protein C-terminus binding; protein heterodimerization activity; protein homodimerization activity; protein kinase B binding; protein kinase binding; protein self-association; transcription coactivator activity; transcription factor binding; ubiquitin binding; ubiquitin protein ligase binding
Biological Process: activation of JNK activity; activation of NF-kappaB transcription factor; adaptive immune response; apoptosis; B cell apoptosis; caspase activation; cell death; cellular defense response; I-kappaB kinase/NF-kappaB cascade; immune system process; immunoglobulin mediated immune response; mast cell activation; negative regulation of mature B cell apoptosis; neural tube closure; positive regulation of apoptosis; positive regulation of caspase activity; positive regulation of interleukin-8 biosynthetic process; positive regulation of phosphorylation; positive regulation of protein ubiquitination; positive regulation of T cell activation; positive regulation of transcription, DNA-dependent; protein heterooligomerization; protein homooligomerization; protein oligomerization; regulation of apoptosis; regulation of T cell receptor signaling pathway; response to food; response to fungus; T cell receptor signaling pathway
Research Articles on Bcl10
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Product Notes
The Mouse Bcl10 bcl10 (Catalog #AAA289750) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289750 ELISA Kit recognizes Mouse Bcl10. It is sometimes possible for the material contained within the vial of "B-cell lymphoma/leukemia 10, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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