SDS-Page
ULBP1 active protein
ULBP1, 26-216aa, Human, His-tag, Baculovirus
Gene Names
ULBP1; N2DL-1; RAET1I; NKG2DL1
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
ULBP1; 26-216aa; Human; His-tag; Baculovirus; NKG2D ligand 1; N2DL-1; NKG2DL1; RAET1I; ULBP1 active protein
Host
Baculovirus
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence
ADLGWVDTHC LCYDFIITPK SRPEPQWCEV QGLVDERPFL HYDCVNHKAK AFASLGKKVN VTKTWEEQTE TLRDVVDFLK GQLLDIQVEN LIPIEPLTLQ ARMSCEHEAH GHGRGSWQFL FNGQKFLLFD SNNRKWTALH PGAKKMTEKW EKNRDVTMFF QKISLGDCKM WLEEFLMYWE QMLDPTKPPS LAPGHHHHHH
Sequence Length
244
Applicable Applications for ULBP1 active protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for ULBP1 active protein
ULBP1, also known as NKG2D ligand 1, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It is unconventional MHC class I-like molecules exploited by viruses and cancer. Its ligand Methylation contributes to immune system evasion in acute myeloid leukemia. It is independent predictors of good prognosis in cervical cancer. Recombinant human ULBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for ULBP1 active protein
References
Baragano Raneros A., et al. (2015) Genes Immun. 16:71-82.; Cerwenka A., et al. (2003) Tissue Antigens. 61:335-343.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23.4kDa (200aa) 28-40kDa (SDS-PAGE under reducing conditions)
NCBI Official Full Name
UL16-binding protein 1 isoform 1
NCBI Official Synonym Full Names
UL16 binding protein 1
NCBI Official Symbol
ULBP1
NCBI Official Synonym Symbols
N2DL-1; RAET1I; NKG2DL1
NCBI Protein Information
UL16-binding protein 1; NKG2D ligand 1
UniProt Protein Name
UL16-binding protein 1
Protein Family
UniProt Gene Name
ULBP1
UniProt Synonym Gene Names
N2DL1; RAET1I; N2DL-1; NKG2DL1
NCBI Description
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Uniprot Description
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Research Articles on ULBP1
1. we show that Simian Virus 40 (SV40)...evades NK cell attack through the down regulation of...ULBP1
Similar Products
Product Notes
The ULBP1 ulbp1 (Catalog #AAA206486) is an Active Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's ULBP1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the ULBP1 ulbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ADLGWVDTHC LCYDFIITPK SRPEPQWCEV QGLVDERPFL HYDCVNHKAK AFASLGKKVN VTKTWEEQTE TLRDVVDFLK GQLLDIQVEN LIPIEPLTLQ ARMSCEHEAH GHGRGSWQFL FNGQKFLLFD SNNRKWTALH PGAKKMTEKW EKNRDVTMFF QKISLGDCKM WLEEFLMYWE QMLDPTKPPS LAPGHHHHHH. It is sometimes possible for the material contained within the vial of "ULBP1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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