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Typical Testing Data/Standard Curve (for reference only)

Rat Beta-secretase 2 ELISA Kit | Bace2 elisa kit

Rat Beta-secretase 2 ELISA Kit

Reactivity
Rat
Synonyms
Beta-secretase 2; Rat Beta-secretase 2 ELISA Kit; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; Bace2; Bace2 elisa kit
Ordering
For Research Use Only!
Reactivity
Rat
Sequence Length
514
Assay Type
Sandwich
Detection Range
0.312-20 ng/ml
Sensitivity
0.177 ng/mL
Intra-Assay CV
<=4.7%
Inter-Assay CV
<=7.6%
Recovery
108%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,858 Da
NCBI Official Full Name
beta-secretase 2
NCBI Official Synonym Full Names
beta-site APP-cleaving enzyme 2
NCBI Official Symbol
Bace2
NCBI Protein Information
beta-secretase 2
UniProt Protein Name
Beta-secretase 2
Protein Family
UniProt Gene Name
Bace2
UniProt Synonym Gene Names
Beta-site APP cleaving enzyme 2
UniProt Entry Name
BACE2_RAT

Uniprot Description

BACE2: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672. Belongs to the peptidase A1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.23.45; Protease; Membrane protein, integral

Cellular Component: cell surface; endoplasmic reticulum; endosome; Golgi apparatus; integral to membrane

Molecular Function: aspartic-type endopeptidase activity; beta-amyloid binding

Biological Process: beta-amyloid metabolic process; membrane protein ectodomain proteolysis; negative regulation of amyloid precursor protein biosynthetic process; protein catabolic process

Research Articles on Bace2

Similar Products

Product Notes

The Rat Bace2 bace2 (Catalog #AAA2886931) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886931 ELISA Kit recognizes Rat Bace2. It is sometimes possible for the material contained within the vial of "Beta-secretase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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