ATPase Class VI Type 11B Recombinant Protein | ATP11B recombinant protein

Recombinant ATPase Class VI Type 11B (ATP11B)

Cat. Num. AAA2123786

• Gene Names: ATP11B; ATPIF; ATPIR
• Applications: SDS-Page, Western Blot
• Purity: >90%
• Synonyms: ATPase Class VI Type 11B; Recombinant ATPase Class VI Type 11B (ATP11B); ATPIF; ATPIR; Probable Phospholipid-Transporting ATPase IF; P4-ATPase flippase complex alpha subunit ATP11B; ATP11B recombinant protein

• Host: E Coli
• Purity/Purification: >90%
• Form/Format: Freeze-dried powder; PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Sequence Positions: Gln78~Asn323
• Sequence Length: 1177

• Applicable Applications for ATP11B recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Source: Prokaryotic expression
• Species: Human
• Tag: N-terminal His Tag
• Subcellular Location: Secreted
• Isoelectric Point: 5.7
• Reconstitution: Reconstitute in PBS or others.
• Preparation and Storage: Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.; Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for ATP11B recombinant protein

Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 62632750
• NCBI GeneID: 23200
• NCBI Accession #: NP_055431
• NCBI GenBank Nucleotide #: NP_055431.1
• UniProt Accession #: Q9Y2G3
• Molecular Weight: Predicted Molecular Mass: 31.3kDa; Accurate Molecular Mass: 33kDa
• NCBI Official Full Name: probable phospholipid-transporting ATPase IF
• NCBI Official Synonym Full Names: ATPase phospholipid transporting 11B (putative)
• NCBI Official Symbol: ATP11B
• NCBI Official Synonym Symbols: ATPIF; ATPIR
• NCBI Protein Information: probable phospholipid-transporting ATPase IF
• UniProt Protein Name: Probable phospholipid-transporting ATPase IF
• Protein Family: Probable phospholipid-transporting ATPase
• UniProt Gene Name: ATP11B
• UniProt Synonym Gene Names: ATPIF; ATPIR; KIAA0956
• UniProt Entry Name: AT11B_HUMAN

NCBI Description

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]

Uniprot Description

ATP11B: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. Interacts with TMEM30A

Protein type: Hydrolase; Transporter, ion channel; Membrane protein, multi-pass; Membrane protein, integral; Transporter; EC 3.6.3.1

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: Golgi apparatus; recycling endosome; membrane; recycling endosome membrane; endoplasmic reticulum; early endosome; integral to membrane; plasma membrane; nuclear inner membrane

Molecular Function: phospholipid-translocating ATPase activity; protein binding; ion transmembrane transporter activity; magnesium ion binding; ATP binding

Biological Process: phospholipid translocation; metabolic process; aminophospholipid transport; ion transport; transmembrane transport