Hydroxyproline Assay Kit
Hydroxyproline assay kit (Alkali hydrolysis method)
Synonyms
Hydroxyproline; Hydroxyproline assay kit (Alkali hydrolysis method); Hydroxyproline assay kit
Samples
Animal serum, plasma, tissue, urine and other samples.
Related Product Information for Hydroxyproline assay kit
Background/Introduction: Hydroxyproline accounts for 13.4% in collagen and very little in elastin, but cannot be found in other proteins. Collagen is mostly distributed in skin, tendon, cartilage, blood vessels, etc. So the amount of hydroxyproline can reflect the collage metabolism of the connective disease. The determination of hydroxyproline in skin is a screening index of anti-aging medicines. The excretion of hydroxyproline will increase with age in development stage, then keep stable after non-development. The hydroxyproline in elderly is less than in the young. When rats suffer from spontaneous hypertension and secondary hypertension, the content of hydroxyproline will increase in their urine. Surgical trauma will result in an increase of hydroxyproline in the urinary excretion. High lipid, low protein, alcoholic poisoning toxicant, malnutrition, or liver cell degeneration and necrosis will lead to the increase of fiber by inflammation which splits liver lobule, leading to cirrhosis of the liver. When the liver fibrosis, the collagen fibers are the mainly increasing composition in liver, which uniquely contains the hydroxyproline. The content of liver hydroxyproline can be converted to the content of the liver collagen, reflecting the degree of liver fibrosis. The decomposition of collagen fiber mainly depends on collagen enzyme and other protease. The hydroxyproline decomposed products will be excreted by the urine. The collagen degradation can be reflected by the content of urinary hydroxyproline. By determining the content of hydroxyproline in the tissue and urine, the degree of fibrosis can be judged, and the preventing and treating drugs can also be screened. This kit can be used to detect the content of hydroxyproline(HYP) in animal serum(plasma),tissue urine etc.
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Product Notes
The Hydroxyproline (Catalog #AAA2540442) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Hydroxyproline, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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