SDS-Page
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
ASH2L recombinant protein
ASH2L Protein
Gene Names
ASH2L; ASH2; Bre2; ASH2L1; ASH2L2
Applications
Methyltransferase Assay
Synonyms
ASH2L; ASH2L Protein; ASH2L2; ASH2L recombinant protein
Host
E Coli
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Applicable Applications for ASH2L recombinant protein
Methyltransferase Assay
Tag
GST
Species
Human
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
SDS-Page
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
SDS-Page
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
Related Product Information for ASH2L recombinant protein
Full-length recombinant human ASH2L was expressed in E Coli cells using an N-terminal GST tag. The gene accession number is BC015936.
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) is part of MLL complexes, consisting of one of seven Set/MLL proteins (SETA, SETB, MLL1 to 5), ASH2L, RBBP5, WDR5, HDPY-30, and others. Possesses histone methyltransferase activity. Specifically methylates 'Lys-4' of histone H3 when the neighboring 'Lys-9' residue is not methylated.
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) is part of MLL complexes, consisting of one of seven Set/MLL proteins (SETA, SETB, MLL1 to 5), ASH2L, RBBP5, WDR5, HDPY-30, and others. Possesses histone methyltransferase activity. Specifically methylates 'Lys-4' of histone H3 when the neighboring 'Lys-9' residue is not methylated.
Product Categories/Family for ASH2L recombinant protein
References
1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56.
2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor alpha gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.
2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor alpha gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,208 Da
NCBI Official Full Name
Homo sapiens ash2 (absent, small, or homeotic)-like (Drosophila), mRNA
NCBI Official Synonym Full Names
ash2 (absent, small, or homeotic)-like (Drosophila)
NCBI Official Symbol
ASH2L
NCBI Official Synonym Symbols
ASH2; Bre2; ASH2L1; ASH2L2
NCBI Protein Information
set1/Ash2 histone methyltransferase complex subunit ASH2; ASH2-like protein
Research Articles on ASH2L
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Product Notes
The ASH2L (Catalog #AAA516568) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ASH2L can be used in a range of immunoassay formats including, but not limited to, Methyltransferase Assay. Researchers should empirically determine the suitability of the ASH2L for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASH2L, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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