Ankyrin Repeat and SOCS Box Protein 13/ASB13 Recombinant Protein | ASB13 recombinant protein

Recombinant Human Ankyrin Repeat and SOCS Box Protein 13/ASB13 Protein (N-6His)

Cat. Num. AAA2552350

• Purity: >90% as determined by reducing SDS-PAGE.
• Synonyms: Ankyrin Repeat and SOCS Box Protein 13/ASB13; Recombinant Human Ankyrin Repeat and SOCS Box Protein 13/ASB13 Protein (N-6His); Ankyrin repeat and SOCS box protein 13; ASB13; ASB13 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by reducing SDS-PAGE.
• Form/Format: Supplied as a 0.2 mum filtered solution of PBS, pH 7.4, 4M Urea.
• Sequence Positions: Met1-Asn278
• Sequence Length: 278

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fusion Tag: N-6His
• Preparation and Storage: Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Related Product Information for ASB13 recombinant protein

Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 22208957
• NCBI GeneID: 79754
• NCBI Accession #: NP_078977.2
• NCBI GenBank Nucleotide #: NM_024701.3
• UniProt Accession #: Q8WXK3; Q96EP7; Q9H8Z1; A8K7Q6; D3DRR2
• Molecular Weight: Molecular Mass: 31.4 kDa; Actual Protein Molecular Mass: 28 kDa
• NCBI Official Full Name: ankyrin repeat and SOCS box protein 13
• NCBI Official Synonym Full Names: ankyrin repeat and SOCS box containing 13
• NCBI Official Symbol: ASB13
• NCBI Protein Information: ankyrin repeat and SOCS box protein 13
• UniProt Protein Name: Ankyrin repeat and SOCS box protein 13
• Protein Family: Ankyrin repeat and SOCS box protein
• UniProt Gene Name: ASB13
• UniProt Synonym Gene Names: ASB-13

NCBI Description

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010]

Uniprot Description

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.