Androgen Receptor (AR) Recombinant Protein | AR recombinant protein
Recombinant Androgen Receptor (AR)
MGHHHHHHSGS-SQCVRM RHLSQEFGWL QITPQEFLCM KALLLFSIIP VDGLKNQKFF DELRMNYIKE LDRIIACKRK NPTSCSRRFY QLTKLLDSVQ PIARELHQFT FDLLIKSHMV SVDFPEMMAE IISVQVPKIL SGKVKPIYFH TQ
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
NCBI Description
binds androgens and activates transcription; required for male sexual development [RGD, Feb 2006]
Uniprot Description
AR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Protein type: Nuclear receptor; DNA-binding; Transcription factor
Cellular Component: protein complex; axon; nuclear chromatin; dendrite; cytoplasm; plasma membrane; nucleus
Molecular Function: protein domain specific binding; ligand-dependent nuclear receptor activity; zinc ion binding; androgen binding; beta-catenin binding; transcription factor binding; androgen receptor activity; protein binding; enzyme binding; androgen receptor binding; DNA binding; sequence-specific DNA binding; chromatin binding; transcription factor activity; receptor binding
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of estrogen receptor signaling pathway; response to insulin stimulus; activation of NF-kappaB transcription factor; negative regulation of integrin biosynthetic process; Leydig cell differentiation; regulation of transcription, DNA-dependent; positive regulation of MAPKKK cascade; regulation of catalytic activity; single fertilization; positive regulation of cell proliferation; male genitalia morphogenesis; positive regulation of integrin biosynthetic process; negative regulation of epithelial cell proliferation; regulation of developmental growth; organ formation; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; in utero embryonic development; multicellular organism growth; male gonad development; protein oligomerization; regulation of transcription from RNA polymerase II promoter; male sex differentiation; fertilization; regulation of gene expression; androgen receptor signaling pathway; regulation of systemic arterial blood pressure; positive regulation of transcription from RNA polymerase III promoter; positive regulation of transcription from RNA polymerase II promoter; spermatogenesis; male somatic sex determination; steroid hormone mediated signaling; cellular process; reproductive structure development; positive regulation of phosphorylation
Research Articles on AR
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Product Notes
The AR ar (Catalog #AAA2009941) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Androgen Receptor (AR) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the AR ar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG S-SQCVRM RHLSQEFGWL QITPQEFLCM KALLLFSIIP VDGLKNQKFF DELRMNYIKE LDRIIACKRK NPTSCSRRFY QLTKLLDSVQ PIARELHQFT FDLLIKSHMV SVDFPEMMAE IISVQVPKIL SGKVKPIYFH TQ. It is sometimes possible for the material contained within the vial of "Androgen Receptor (AR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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