Apolipoprotein H Recombinant Protein
Apolipoprotein H, Recombinant, Human (beta 2 Glycoprotein 1, ApoHb2gp1)
Purity
Highly Purified90% (SDS-PAGE)
Synonyms
Apolipoprotein H; Recombinant; Human (beta 2 Glycoprotein 1; ApoHb2gp1); Apolipoprotein H recombinant protein
Host
Sf9 insect cells
Purity/Purification
Highly Purified
90% (SDS-PAGE)
90% (SDS-PAGE)
Form/Format
Supplied as a liquid in 16mM HEPES buffer, pH 7.2, 200mM sodium chloride and 20% glycerol.
Application Notes
Western-Blot with monoclonal anti-hexa-His-tag antibody and Goodpasture patient sera.
Preparation and Storage
-20 degree C
Stability: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze-thaw cycles.
Stability: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze-thaw cycles.
Related Product Information for Apolipoprotein H recombinant protein
Beta2 Glycoprotein I (b2GPI) is a serum protein with a single polypeptide chain consisting of 326 amino acids and having a molecular weight of 50kD. The protein is also known by the alternative name Apolipoprotein H (ApoH) which gives an indication of its phospholipid binding function. Since the detection of 2 Glycoprotein I as a target of antiphospholipid antibodies in 1990 the discussion about the clinical relevance of beta2 GP I is still controversial. It is well established that anticardiolipin antibodies are a very heterogeneous group and that beta 2 GP I is only one of several potential targets for anticardiolipin antibodies. Nevertheless it is generally accepted that the binding of 2 GP I to anionic lipids or surface is essential for the differential detection of anticardiolipin antibodies associated with autoimmune diseases (versus those associated with infectious diseases like syphilis, tuberculosis, AIDS, etc). The close relationship of beta2-GP1 antibodies and cardiolipin antibodies may indicate that the b2 GP I isotypes have the same clinical relevance as the cardiolipin isotypes, where IgM, IgG and IgA autoantibodies have been observed and are routinely determined targets. b2GP-1 antibodies and anticardiolipin antibodies can be detected in patients with arterial and venous thrombosis, recurrent fetal loss, thrombosis and SLE. The titers of anticardiolipin and anti-beta2 GP I antibodies usually fluctuate sufficiently that they cannot be used for disease monitoring.
Product Categories/Family for Apolipoprotein H recombinant protein
NCBI and Uniprot Product Information
Uniprot Description
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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Product Notes
The Apolipoprotein H (Catalog #AAA638110) is a Recombinant Protein produced from Sf9 insect cells and is intended for research purposes only. The product is available for immediate purchase. Western-Blot with monoclonal anti-hexa-His-tag antibody and Goodpasture patient sera. Researchers should empirically determine the suitability of the Apolipoprotein H for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apolipoprotein H, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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