DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) Recombinant Protein | APOBEC3G recombinant protein
Recombinant Macaca fascicularis DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G); Recombinant Macaca fascicularis DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G); APOBEC3G recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-384, Full length protein
Sequence
MQPQYRNTVERMYRGTFFYNFNNRPILSRRNTVWLCYEVKTRGPSMPTWDTKIFRGQVLRSKAKYHPEMRFLHWFREWRQLHHDQEYKVTWYVSWSPCTRCANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILCQKRGGLHATMKIMNYNEFQDCWNKFVDGGGKPFKPRNNLPKHYTLLQATLGELLRHLMDPGTFTSNFNNKPWVSGQHETYLCYKVERLHNDTWVPLNQHRGFLRNQAPNIHGFPKGRHAELCFLDLIPFWKLDGQQYRVTCFTSWSPCFSCAQEMAKFISNNEHLSLCIFAARIYDDQGRYQEGLRTLHRDGAKIAMMNYSEFKHCWDTFVDRQGRPFQPWDGLDEHSQALSERLRAILQNQGN
Sequence Length
384
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
45,842 Da
NCBI Official Full Name
DNA dC->
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3G
Protein Family
UniProt Gene Name
APOBEC3G
Uniprot Description
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA ().
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Product Notes
The APOBEC3G apobec3g (Catalog #AAA1367391) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-384, Full length protein. The amino acid sequence is listed below: MQPQYRNTVE RMYRGTFFYN FNNRPILSRR NTVWLCYEVK TRGPSMPTWD TKIFRGQVLR SKAKYHPEMR FLHWFREWRQ LHHDQEYKVT WYVSWSPCTR CANSVATFLA KDPKVTLTIF VARLYYFWKP DYQQALRILC QKRGGLHATM KIMNYNEFQD CWNKFVDGGG KPFKPRNNLP KHYTLLQATL GELLRHLMDP GTFTSNFNNK PWVSGQHETY LCYKVERLHN DTWVPLNQHR GFLRNQAPNI HGFPKGRHAE LCFLDLIPFW KLDGQQYRVT CFTSWSPCFS CAQEMAKFIS NNEHLSLCIF AARIYDDQGR YQEGLRTLHR DGAKIAMMNY SEFKHCWDTF VDRQGRPFQP WDGLDEHSQA LSERLRAILQ NQGN. It is sometimes possible for the material contained within the vial of "DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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