Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 ELISA Kit | APOBEC1 elisa kit
Human C->U-editing enzyme APOBEC-1, APOBEC1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008]
Uniprot Description
APOBEC1: apolipoprotein B mRNA editing enzyme. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. Expressed exclusively in the small intestine.
Protein type: Hydrolase; RNA-binding; RNA processing; EC 3.5.4.-; Cell cycle regulation
Chromosomal Location of Human Ortholog: 12p13.1
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: protein binding; zinc ion binding; RNA binding; AU-rich element binding; cytidine deaminase activity
Biological Process: response to drug; mRNA stabilization; response to osmotic stress; regulation of cell proliferation; RNA processing; response to ethanol; cellular response to insulin stimulus; cytidine to uridine editing; lipoprotein transport; response to zinc ion; lipoprotein biosynthetic process; mRNA modification; response to gamma radiation; gene expression; cytidine deamination; lipid metabolic process; response to calcium ion; mRNA processing; defense response to virus
Research Articles on APOBEC1
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Product Notes
The Human APOBEC1 apobec1 (Catalog #AAA9332467) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332467 ELISA Kit recognizes Human APOBEC1. It is sometimes possible for the material contained within the vial of "apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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