Acylamino-acid-releasing enzyme (APEH) Recombinant Protein | APEH recombinant protein

Recombinant Pig Acylamino-acid-releasing enzyme (APEH), partial

Gene Names

APEH; AAP; APH; AARE

Purity

Greater or equal to 85% purity as determined by SDS-PAGE.

Synonyms

Acylamino-acid-releasing enzyme (APEH); Recombinant Pig Acylamino-acid-releasing enzyme (APEH); partial; APEH recombinant protein

Ordering
Cat. Num. AAA955572 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE.

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Sequence Length

732

Species

Sus scrofa (Pig)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for APEH recombinant protein

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

NCBI and Uniprot Product Information

NCBI GI #

47522644

NCBI GeneID

396961

NCBI Accession #

NP_999088.1

NCBI GenBank Nucleotide #

NM_213923.1

UniProt Accession #

P19205; Q9TS46

Molecular Weight

81,244 Da

NCBI Official Full Name

acylamino-acid-releasing enzyme

NCBI Official Symbol

APEH

NCBI Official Synonym Symbols

AAP; APH; AARE

NCBI Protein Information

acylamino-acid-releasing enzyme

UniProt Protein Name

Acylamino-acid-releasing enzyme

Protein Family

Acylamino-acid-releasing enzyme

UniProt Gene Name

APEH

UniProt Synonym Gene Names

AARE; APH

Uniprot Description

This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

Research Articles on APEH

1. crystallographic analysis of porcine acylaminoacyl peptidase

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Product Notes

The APEH apeh (Catalog #AAA955572) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Acylamino-acid-releasing enzyme (APEH), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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