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AP3S1 recombinant protein

AP3s1, Recombinant, Human (Adaptor-related Protein Complex 3 sigma 1, Clathrin Assembly Protein Complex 3)

Gene Names
AP3S1; CLAPS3; Sigma3A
Purity
Highly Purified
95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Synonyms
AP3s1; Recombinant; Human (Adaptor-related Protein Complex 3 sigma 1; Clathrin Assembly Protein Complex 3); AP3S1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Highly Purified
95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Form/Format
Supplied as a liquid in 10mM Tris, pH 8.0, 0.01% Triton X-100, 0.002% sodium azide and 10mM DTT.
Application Notes
ELISA, MS, Western Blotting
Preparation and Storage
-20 degree C
Stability: Recombinant P3S2 although stable at 140C for 1 week, should be stored desiccated below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Related Product Information for AP3S1 recombinant protein
Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

Recombinant Human AP3S1 produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids (1-193) and having a total molecular mass of 22.2kD. Recombinant AP3S1 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
Product Categories/Family for AP3S1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22.2kD
NCBI Official Full Name
AP-3 complex subunit sigma-1
NCBI Official Synonym Full Names
adaptor-related protein complex 3, sigma 1 subunit
NCBI Official Symbol
AP3S1
NCBI Official Synonym Symbols
CLAPS3; Sigma3A
NCBI Protein Information
AP-3 complex subunit sigma-1; sigma3A-adaptin; sigma-3A-adaptin; sigma-adaptin 3a; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-3A; adapter-related protein complex 3 sigma-1 subunit; clathrin-associated/assembly/adapter protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD)
UniProt Protein Name
AP-3 complex subunit sigma-1
Protein Family
UniProt Gene Name
AP3S1
UniProt Synonym Gene Names
CLAPS3; Sigma3A-adaptin
UniProt Entry Name
AP3S1_HUMAN

Uniprot Description

AP3S1: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes small subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q22

Cellular Component: Golgi apparatus; transport vesicle; cytoplasmic vesicle membrane; AP-type membrane coat adaptor complex

Molecular Function: protein binding; transporter activity; protein transporter activity

Biological Process: intracellular protein transport; anterograde synaptic vesicle transport; insulin receptor signaling pathway; anterograde axon cargo transport

Research Articles on AP3S1

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Product Notes

The AP3S1 ap3s1 (Catalog #AAA637423) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. ELISA, MS, Western Blotting. Researchers should empirically determine the suitability of the AP3S1 ap3s1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AP3s1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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