Human adaptor-related protein complex 3, delta 1 subunit ELISA Kit | AP3D1 elisa kit

Human AP-3 complex subunit delta-1, AP3D1 ELISA Kit

Cat. Num. AAA9338531

• Gene Names: AP3D1; ADTD; hBLVR
• Reactivity: Human
• Synonyms: adaptor-related protein complex 3; delta 1 subunit; Human AP-3 complex subunit delta-1; AP3D1 ELISA Kit; Human AP-3 complex subunit delta-1 (AP3D1) ELISA kit; ADTD; hBLVR; AP-3 complex delta subunit; partial CDS; adaptin; delta; delta adaptin; delta-adaptin; subunit of putative vesicle coat adaptor complex AP-3; AP3D1 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 387849337
• NCBI GeneID: 8943
• NCBI Accession #: NP_001248755.1
• NCBI GenBank Nucleotide #: NM_001261826.1
• UniProt Accession #: O14617; O00202; O75262; Q59HF5; Q96G11; Q9H3C6
• Molecular Weight: 130,158 Da
• NCBI Official Full Name: AP-3 complex subunit delta-1 isoform 3
• NCBI Official Synonym Full Names: adaptor-related protein complex 3, delta 1 subunit
• NCBI Official Symbol: AP3D1
• NCBI Official Synonym Symbols: ADTD; hBLVR
• NCBI Protein Information: AP-3 complex subunit delta-1; delta adaptin; adaptin, delta; delta-adaptin, partial CDS; AP-3 complex delta subunit, partial CDS; adapter-related protein complex 3 subunit delta-1; adaptor-related protein complex 3 subunit delta-1; subunit of putative vesicle coat adaptor complex AP-3
• UniProt Protein Name: AP-3 complex subunit delta-1
• Protein Family: AP-3 complex
• UniProt Gene Name: AP3D1
• UniProt Synonym Gene Names: PRO0039
• UniProt Entry Name: AP3D1_HUMAN

NCBI Description

The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

AP3D1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes large subunit family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; membrane coat; membrane; lysosomal membrane; terminal button; endosome membrane

Molecular Function: transporter activity

Biological Process: intracellular protein transport; melanosome organization and biogenesis; protein localization in organelle; anterograde synaptic vesicle transport; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; synaptic vesicle membrane organization and biogenesis; positive regulation of NK T cell differentiation; anterograde axon cargo transport; eye pigment biosynthetic process