SDS-Page
ANTXR2 recombinant protein
ANTXR2, 34-317aa, Human, His tag, E Coli
Gene Names
ANTXR2; HFS; ISH; JHF; CMG2; CMG-2
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
ANTXR2; 34-317aa; Human; His tag; E Coli; Anthrax toxin receptor 2; CMG-2; m CMG2; HFS; ISH; JHF; ANTXR2 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSQEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN
Sequence Length
489
Applicable Applications for ANTXR2 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for ANTXR2 recombinant protein
ANTXR2 is called anthrax toxin receptor 2 because it allows the toxin that causes anthrax to attach to cells and trigger disease. This protein is involved in the formation of tiny blood vessels (capillaries). It is also important for maintaining the structure of basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Recombinant human ANTXR2 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for ANTXR2 recombinant protein
References
Scobie HM, A. et al. (2003) Proc Natl Acad Sci u S A. 100 : 5170-5174.; Abrami L. et al. (2003) J. Cell Biol. 160 : 321-328;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33.0 kDa (307aa) confirmed by MALDI-TOF
NCBI Official Full Name
anthrax toxin receptor 2 isoform 2
NCBI Official Synonym Full Names
anthrax toxin receptor 2
NCBI Official Symbol
ANTXR2
NCBI Official Synonym Symbols
HFS; ISH; JHF; CMG2; CMG-2
NCBI Protein Information
anthrax toxin receptor 2
UniProt Protein Name
Anthrax toxin receptor 2
Protein Family
UniProt Gene Name
ANTXR2
UniProt Synonym Gene Names
CMG2; CMG-2
NCBI Description
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Uniprot Description
Necessary for cellular interactions with laminin and the extracellular matrix.
Research Articles on ANTXR2
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Product Notes
The ANTXR2 antxr2 (Catalog #AAA205735) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's ANTXR2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the ANTXR2 antxr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSQEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN. It is sometimes possible for the material contained within the vial of "ANTXR2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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