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Angiopoietin-related Protein 7/ANGPTL7 Biotinylated Recombinant Protein | ANGPTL7 recombinant protein

Recombinant Human Angiopoietin-related Protein 7/ANGPTL7 (C-10His-Avi) Biotinylated

Gene Names
ANGPTL7; AngX; CDT6; dJ647M16.1; RP4-647M16.2
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
Angiopoietin-related Protein 7/ANGPTL7 Biotinylated; Recombinant Human Angiopoietin-related Protein 7/ANGPTL7 (C-10His-Avi) Biotinylated; Angiopoietin-related protein 7; Angiopoietin-like factor; Angiopoietin-like protein 7; Cornea-derived transcript 6 protein; ANGPTL7; CDT6; ANGPTL7 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
Sequence
Gln27-Pro346
Species
Human
Tag
C-10His-Avi
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Biotinylated Recombinant Human Angiopoietin-related Protein 7 is produced by our Mammalian expression system and the target gene encoding Gln27-Pro346 is expressed with a 10His, Avi tag at the C-terminus.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.

SDS-Page

SDS-Page
Related Product Information for ANGPTL7 recombinant protein
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL7 shares 89% aa sequence identity with mouse and rat ANGPTL7. It is secreted as a 45-50kDa monomer that forms disulfide-linked homotrimers and tetramers via the coiled coil domain. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Its production is up-regulated in trabecular meshwork cells by glucocorticoids and TGF-beta and in cartilage by TNF-alpha. Overexpression of ANGPTL7 in trabecular meshwork cells inhibits the production of collagen and proteoglycans. When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis.
Product Categories/Family for ANGPTL7 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,018 Da
NCBI Official Full Name
angiopoietin-related protein 7
NCBI Official Synonym Full Names
angiopoietin-like 7
NCBI Official Symbol
ANGPTL7
NCBI Official Synonym Symbols
AngX; CDT6; dJ647M16.1; RP4-647M16.2
NCBI Protein Information
angiopoietin-related protein 7; angiopoietin-like protein 7; angiopoietin-like factor (CDT6); cornea-derived transcript 6 protein
UniProt Protein Name
Angiopoietin-related protein 7
UniProt Gene Name
ANGPTL7
UniProt Synonym Gene Names
CDT6
UniProt Entry Name
ANGL7_HUMAN

Uniprot Description

ANGPTL7:

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: extracellular region

Biological Process: response to oxidative stress

Research Articles on ANGPTL7

Similar Products

Product Notes

The ANGPTL7 angptl7 (Catalog #AAA2569203) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln27-Pro3 46. It is sometimes possible for the material contained within the vial of "Angiopoietin-related Protein 7/ANGPTL7 Biotinylated, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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