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APC13 Blocking Peptide | ANAPC13 blocking peptide

APC13 Peptide

Gene Names
ANAPC13; SWM1; APC13
Applications
Blocking (BL)
Synonyms
APC13; APC13 Peptide; SWM1; Anaphase-promoting complex subunit 13; Cyclosome subunit 13; anaphase promoting complex subunit 13; ANAPC13 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
74
Applicable Applications for ANAPC13 blocking peptide
Blocking (BL)
Application Notes
APC13 peptide is used for blocking the activity of APC13 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
17 amino acids near the center of human APC13.
Preparation and Storage
Store APC13 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
8,521 Da
NCBI Official Full Name
anaphase-promoting complex subunit 13
NCBI Official Synonym Full Names
anaphase promoting complex subunit 13
NCBI Official Symbol
ANAPC13
NCBI Official Synonym Symbols
SWM1; APC13
NCBI Protein Information
anaphase-promoting complex subunit 13; cyclosome subunit 13
UniProt Protein Name
Anaphase-promoting complex subunit 13
UniProt Gene Name
ANAPC13
UniProt Synonym Gene Names
APC13
UniProt Entry Name
APC13_HUMAN

NCBI Description

This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]

Uniprot Description

APC13: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC13 family.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 3q22.2

Cellular Component: anaphase-promoting complex

Biological Process: mitosis; cell division

Research Articles on ANAPC13

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Product Notes

The ANAPC13 anapc13 (Catalog #AAA152201) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's APC13 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). APC13 peptide is used for blocking the activity of APC13 antibody. Researchers should empirically determine the suitability of the ANAPC13 anapc13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APC13, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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