Human anaphase promoting complex subunit 11 ELISA Kit | ANAPC11 elisa kit
Human Anaphase-promoting complex subunit 11, ANAPC11 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
APC11: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. Belongs to the RING-box family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ligase; Cell cycle regulation; EC 6.3.2.-; Ubiquitin ligase; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: nucleoplasm; anaphase-promoting complex; nucleolus; cytosol
Molecular Function: zinc ion binding; ubiquitin-protein ligase activity
Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; mitosis; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; cell division; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle spindle assembly checkpoint; protein ubiquitination; mitotic cell cycle
Research Articles on ANAPC11
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Product Notes
The Human ANAPC11 anapc11 (Catalog #AAA9318531) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318531 ELISA Kit recognizes Human ANAPC11. It is sometimes possible for the material contained within the vial of "anaphase promoting complex subunit 11, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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