THO complex subunit 4-A (alyref-a) Recombinant Protein | alyref-a recombinant protein
Recombinant Xenopus laevis THO complex subunit 4-A (alyref-a)
Gene Names
alyref.L; ALY; thoc4; Tho4-A; alyref; thoc4-a; alyref-a
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
THO complex subunit 4-A (alyref-a); Recombinant Xenopus laevis THO complex subunit 4-A (alyref-a); alyref-a recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-256, Full length protein
Sequence
MGDKMDMSLDDIIKLNRSQRPSGRGRGGGRGARGGSARGGAGGRIGGGRGGGAPGVGGPMRSRPVLSRGGRNRPTPYSRPKQLPDKWQHDLFDSGFGAGAGMETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIEAQRRPIQSQSRGGGVTRPRGGTLGFASGNRRGRGGNRGRGRGAGRNPKQQLSAEELDAQLDAYNARMDTS
Sequence Length
256
Species
Xenopus laevis (African clawed frog)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,014 Da
NCBI Official Full Name
THO complex subunit 4-A
NCBI Official Synonym Full Names
Aly/REF export factor L homeolog
NCBI Official Symbol
alyref.L
NCBI Official Synonym Symbols
ALY; thoc4; Tho4-A; alyref; thoc4-a; alyref-a
NCBI Protein Information
THO complex subunit 4-A
UniProt Protein Name
THO complex subunit 4-A
Protein Family
UniProt Gene Name
alyref-a
UniProt Synonym Gene Names
thoc4-a; Tho4-A
Uniprot Description
Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. Involved in the nuclear export of intronless mRNA. Involved in transcription elongation and genome stability ().
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Product Notes
The alyref-an alyref-a (Catalog #AAA1352431) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-256, Full length protein. The amino acid sequence is listed below: MGDKMDMSLD DIIKLNRSQR PSGRGRGGGR GARGGSARGG AGGRIGGGRG GGAPGVGGPM RSRPVLSRGG RNRPTPYSRP KQLPDKWQHD LFDSGFGAGA GMETGGKLLV SNLDFGVSDA DIQELFAEFG TLKKAAVHYD RSGRSLGTAD VHFERKADAL KAMKQYNGVP LDGRPMNIQL VTSQIEAQRR PIQSQSRGGG VTRPRGGTLG FASGNRRGRG GNRGRGRGAG RNPKQQLSAE ELDAQLDAYN ARMDTS. It is sometimes possible for the material contained within the vial of "THO complex subunit 4-A (alyref-a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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