Mouse alkB, alkylation repair homolog 2 (E. coli) ELISA Kit | ALKBH2 elisa kit
Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ALKBH2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ALKBH2: Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1- ethenoadenine (in vitro). Has strong preference for double- stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. Belongs to the alkB family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage; Demethylase; Hydrolase; EC 1.14.11.33; Oxidoreductase
Cellular Component: nucleoplasm; microtubule cytoskeleton; nucleus
Molecular Function: dioxygenase activity; ferrous iron binding; endonuclease activity; metal ion binding; exonuclease activity; DNA-N1-methyladenine dioxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity; DNA demethylase activity
Biological Process: DNA dealkylation; DNA repair; response to DNA damage stimulus
Research Articles on ALKBH2
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Product Notes
The Mouse ALKBH2 alkbh2 (Catalog #AAA9325812) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325812 ELISA Kit recognizes Mouse ALKBH2. It is sometimes possible for the material contained within the vial of "alkB, alkylation repair homolog 2 (E. coli), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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