Duck Aldolase A, Fructose Bisphosphate ELISA Kit | ALDOA elisa kit

Duck Aldolase A, Fructose Bisphosphate ELISA Kit

• Gene Names: ALDOA; ALDA; GSD12
• Reactivity: Duck
• Synonyms: Aldolase A; Fructose Bisphosphate; Duck Aldolase A; Fructose Bisphosphate ELISA Kit; ALDOA elisa kit

• Reactivity: Duck

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 49456715
• NCBI GeneID: 226
• UniProt Accession #: P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2; B4DXI7
• Molecular Weight: 39,420 Da
• NCBI Official Full Name: ALDOA
• NCBI Official Synonym Full Names: aldolase A, fructose-bisphosphate
• NCBI Official Symbol: ALDOA
• NCBI Official Synonym Symbols: ALDA; GSD12
• NCBI Protein Information: fructose-bisphosphate aldolase A; muscle-type aldolase; lung cancer antigen NY-LU-1; fructose-1,6-bisphosphate triosephosphate-lyase
• UniProt Protein Name: Fructose-bisphosphate aldolase A
• Protein Family: Fructose-bisphosphate aldolase
• UniProt Gene Name: ALDOA
• UniProt Synonym Gene Names: ALDA
• UniProt Entry Name: ALDOA_HUMAN

NCBI Description

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

Uniprot Description

ALDOA: a glycolytic enzyme that catalyzes D-fructose 1,6-bisphosphate -> glycerone phosphate + D-glyceraldehyde 3-phosphate. Three forms of aldolase are found in vertebrates - aldolase A in muscle, aldolase B in liver and aldolase C in brain.

Protein type: Lyase; EC 4.1.2.13; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Mitochondrial

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: I band; extracellular space; membrane; extracellular region; M band; cytosol; nucleus; actin cytoskeleton

Molecular Function: tubulin binding; identical protein binding; protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity; actin binding

Biological Process: platelet activation; glycolysis; striated muscle contraction; actin filament organization; glucose metabolic process; pathogenesis; gluconeogenesis; protein homotetramerization; muscle maintenance; fructose 1,6-bisphosphate metabolic process; regulation of cell shape; platelet degranulation; ATP biosynthetic process; carbohydrate metabolic process; blood coagulation; fructose metabolic process

Disease: Glycogen Storage Disease Xii