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Rat aldo-keto reductase family 1, member A1 (aldehyde reductase) ELISA Kit | AKR1A1 elisa kit

Rat Alcohol dehydrogenase [NADP+], AKR1A1 ELISA Kit

Gene Names
Akr1a1; Akr1a4
Reactivity
Rat
Synonyms
aldo-keto reductase family 1; member A1 (aldehyde reductase); Rat Alcohol dehydrogenase [NADP+]; AKR1A1 ELISA Kit; Rat Alcohol dehydrogenase [NADP+] (AKR1A1) ELISA kit; ALDR1; ALR; ARM; DD3; MGC12529; MGC1380; OTTHUMP00000009240; alcohol dehydrogenase; aldehyde reductase; member A1; dihydrodiol dehydrogenase 3; AKR1A1 elisa kit
Ordering
For Research Use Only!
Reactivity
Rat
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,506 Da
NCBI Official Full Name
alcohol dehydrogenase
NCBI Official Synonym Full Names
aldo-keto reductase family 1, member A1 (aldehyde reductase)
NCBI Official Symbol
Akr1a1
NCBI Official Synonym Symbols
Akr1a4
NCBI Protein Information
alcohol dehydrogenase [NADP(+)]; alcohol dehydrogenase [NADP(+)]; aldehyde reductase; 3-DG-reducing enzyme; aldo-keto reductase family 1 member A1
UniProt Protein Name
Alcohol dehydrogenase [NADP(+)]
Protein Family
UniProt Gene Name
Akr1a1
UniProt Synonym Gene Names
Alr
UniProt Entry Name
AK1A1_RAT

NCBI Description

enzyme that catalyzes the NADPH-dependent reduction of 3-deoxyglucosone; important for detoxifying 3-deoxyglucosone when it is formed through the Maillard reaction in vivo [RGD, Feb 2006]

Uniprot Description

AKR1A1: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.2; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase

Cellular Component: extracellular space; apical plasma membrane; cytosol

Molecular Function: L-glucuronate reductase activity; aldehyde reductase activity; alcohol dehydrogenase (NADP+) activity

Biological Process: L-ascorbic acid biosynthetic process; aldehyde catabolic process; D-glucuronate catabolic process

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Product Notes

The Rat AKR1A1 akr1a1 (Catalog #AAA9328466) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328466 ELISA Kit recognizes Rat AKR1A1. It is sometimes possible for the material contained within the vial of "aldo-keto reductase family 1, member A1 (aldehyde reductase), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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