Adenylate Kinase 5 Recombinant Protein | AK5 recombinant protein

Recombinant Human Adenylate Kinase 5

Cat. Num. AAA144768

• Gene Names: AK5; AK6
• Purity: Greater than 85% as determined by SDS-PAGE.
• Synonyms: Adenylate Kinase 5; Recombinant Human Adenylate Kinase 5; AK5 Human; Adenylate Kinase 5 Human Recombinant; Adenylate kinase isoenzyme 5; AK 5; ATP-AMP transphosphorylase 5; AK5; AK6; AK5 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 85% as determined by SDS-PAGE.
• Form/Format: AK5 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT.; Sterile filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMNTNDA KEYMARREIP QLFESLLNGL MCSKPEDPVE YLESCLQKVK ELGGCDKVKW DTFVSQEKKT LPPLNGGQSR RSFLRNVMPG NSNFPYRRYD RLPPIHQFSI ESDTDLSETA ELIEEYEVFD PTRPRPKIIL VIGGPGSGKG TQSLKIAERY GFQYISVGEL LRKKIHSTSS NRKWSLIAKI ITTGELAPQE TTITEIKQKL MQIPDEEGIV IDGFPRDVAQ ALSFEDQICT PDLVVFLACA NQRLKERLLK RAEQQGRPDD NVKATQRRLM NFKQNAAPLV KYFQEKGLIM TFDADRDEDE VFYDISMAVD NKLFPNKEAA AGSSDLDPSM ILDTGEIIDT GSDYEDQGDD QLNVFGEDTM GGFMEDLRKC KIIFIIGGPG SGKGTQCEKL VEKYGFTHLS TGELLREELA SESERSKLIR DIMERGDLVP SGIVLELLKE AMVASLGDTR GFLIDGYPRE VKQGEEFGRR IGDPQLVICM DCSADTMTNR LLQRSRSSLP VDDTTKTIAK RLEAYYRASI PVIAYYETKT QLHKINAEGT PEDVFLQLCT AIDSIF
• Sequence Length: 536

• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Related Product Information for AK5 recombinant protein

Description: AK5 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 586 amino acids (1-562 a.a.) and having a molecular mass of 65.9kDa.AK5 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Adenylate kinase isoenzyme 5 (AK5) belongs to the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. AK5 is related to the UMP/CMP kinase of several species. AK5 is located in the cytosol and expressed exclusively in the brain.

Product Categories/Family for AK5 recombinant protein

Protein Kinases; Enzymes; Adenylate Kinase

NCBI and Uniprot Product Information

• NCBI GI #: 28144899
• NCBI GeneID: 26289
• NCBI Accession #: NP_036225.2
• NCBI GenBank Nucleotide #: NM_012093.3
• UniProt Accession #: Q9Y6K8; Q5U622; Q6FH66; Q7Z4T5; Q86YS0; Q8N464; Q96EC9
• Molecular Weight: 60,315 Da
• NCBI Official Full Name: adenylate kinase isoenzyme 5 isoform 2
• NCBI Official Synonym Full Names: adenylate kinase 5
• NCBI Official Symbol: AK5
• NCBI Official Synonym Symbols: AK6
• NCBI Protein Information: adenylate kinase isoenzyme 5; AK 5; ATP-AMP transphosphorylase 5; adenylate kinase 6
• UniProt Protein Name: Adenylate kinase isoenzyme 5
• Protein Family: Adenylate kinase
• UniProt Gene Name: AK5
• UniProt Synonym Gene Names: AK 5
• UniProt Entry Name: KAD5_HUMAN

NCBI Description

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

AK5: Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Belongs to the adenylate kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.4.6; Nucleotide Metabolism - purine; EC 2.7.4.3; Kinase, other

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: cytoplasm; microtubule organizing center; cytosol

Molecular Function: nucleoside kinase activity; nucleoside diphosphate kinase activity; adenylate kinase activity; ATP binding

Biological Process: ATP metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleoside triphosphate biosynthetic process; pyrimidine ribonucleotide biosynthetic process; ADP biosynthetic process; nucleoside diphosphate phosphorylation; dADP biosynthetic process