Human Putative adenosylhomocysteinase 2 ELISA Kit | AHCYL1 elisa kit

Human Putative adenosylhomocysteinase 2 ELISA Kit

Cat. Num. AAA9426921

• Gene Names: AHCYL1; DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
• Reactivity: Human
• Synonyms: Putative adenosylhomocysteinase 2; Human Putative adenosylhomocysteinase 2 ELISA Kit; AdoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1; AHCYL1 elisa kit

• Reactivity: Human

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Detection Range: 78-5000 pg/mL
• Assay Time: 3-5h
• Sample Volume: 100T
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 4 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 336455095
• NCBI GeneID: 10768
• NCBI Accession #: NP_001229602.1
• NCBI GenBank Nucleotide #: NM_001242673.1
• UniProt Accession #: O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84; B4E168
• Molecular Weight: 53,753 Da
• NCBI Official Full Name: S-adenosylhomocysteine hydrolase-like protein 1 isoform b
• NCBI Official Synonym Full Names: adenosylhomocysteinase like 1
• NCBI Official Symbol: AHCYL1
• NCBI Official Synonym Symbols: DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
• NCBI Protein Information: S-adenosylhomocysteine hydrolase-like protein 1; adenosylhomocysteinase 2
• UniProt Protein Name: S-adenosylhomocysteine hydrolase-like protein 1
• Protein Family: Putative adenosylhomocysteinase
• UniProt Gene Name: AHCYL1
• UniProt Synonym Gene Names: IRBIT; AdoHcyase 2

NCBI Description

The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

AHCYL1: an inositol 1,4,5-trisphosphate receptor 1 (IP3R1)-binding protein that inhibits IP3 binding to IP3R1 and IP3-induced intracellular Ca2 release. Suppresses the activation of IP3R1 via a phosphorylation-dependent mechanism. Also binds the Na/HCO3 cotransporter 1 (SLC4A4) and may play an important role in pH regulation. Contains a domain homologous to S-adenosylhomocysteine hydrolase (SAHH), although it is reported to possess no hydrolase activity. Its expression is induced in cultured monocytes when they are differentiated into dendritic cells (DC) by exposure to GM-CSF and IL-4.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 3.3.1.1; Hydrolase; Other Amino Acids Metabolism - selenoamino acid

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: apical plasma membrane; cytoplasm; cytosol; endoplasmic reticulum membrane

Molecular Function: adenosylhomocysteinase activity; identical protein binding; protein binding

Biological Process: mRNA polyadenylation; regulation of ion transmembrane transporter activity; regulation of mRNA 3'-end processing; response to calcium ion; S-adenosylmethionine cycle