Adenosine monophosphate-protein transferase FICD homolog (GJ12914) Recombinant Protein | DvirGJ12914 recombinant protein
Recombinant Drosophila virilis Adenosine monophosphate-protein transferase FICD homolog (GJ12914)
NCBI and Uniprot Product Information
Uniprot Description
Function: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins
By similarity.
Catalytic activity: ATP + [protein] = diphosphate + [protein]-AMP.
Enzyme regulation: Adenylyltransferase activity is inhibited by the inhibitory helix present at the N-terminus: Glu-236 binds ATP and competes with ATP-binding at Arg-375, thereby preventing adenylyltransferase activity. Activation dissociates ATP-binding from Glu-236, allowing ordered binding of the entire ATP moiety with the alpha-phosphate in an orientation that is productive for accepting an incoming target hydroxyl side chain
By similarity.
Subcellular location: Membrane; Single-pass membrane protein
Potential.
Domain: The fido domain mediates the adenylyltransferase activity
By similarity.
Sequence similarities: Belongs to the fic family.Contains 1 fido domain.Contains 2 TPR repeats.
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Product Notes
The DvirGJ12914 (Catalog #AAA1092433) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-485. The amino acid sequence is listed below: MAKAKAKQEP QQQRQTLQAT YRFVLFFIAG SLAAFAFHAL TSSTGSLMGW RLRLHHLPTA HYLQTRDEFA VYSVDELNAF KEFYDKSISD SVGASFTEAE QTNIKEAMGA LRLAQEMYMA GKDDKAARLF EHALALAPKH PEVLLRYGEF LEHNQRNIVL ADQYYFQALC ISPSNSEALA NRQRTADVVQ TLDERRLISL DEKRDALSAI HEANSALRRA KKEAYFQHIY HSVGIEGNTM TLAQTRSVLE TRMAVDGKSI DEHNEILGMD LAMKYINASL VQKLEITLKD ILELHRRVLG HVDPIEGGEF RRNQVYVGGH VPPGPGDLAI LMQRFEHWLN SEHSSSLHPV NYAALAHYKL VHIHPFVDGN GRTSRLLMNT LLMRAGYPPV IIPKQQRSKY YHFLKLANEG DIRPFVRFIA DCTEKTLDLY LWATSDLPQQ IPMLIQTENE GHVLAQLQPH IAQSIPELHE SGSGSGSGAD PIRVP. It is sometimes possible for the material contained within the vial of "Adenosine monophosphate-protein transferase FICD homolog (GJ12914), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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