CECR1 recombinant protein

CECR1, 30-511aa, Human, His tag, Baculovirus

Cat. Num. AAA206273

• Gene Names: ADA2; PAN; ADGF; CECR1; IDGFL; SNEDS
• Applications: SDS-Page
• Purity: > 90% by SDS-PAGE
• Synonyms: CECR1; 30-511aa; Human; His tag; Baculovirus; Adenosine deaminase CECR1 isoform; ADA2; ADGF; IDGFL; PAN; SNEDS; CECR1 recombinant protein

• Host: Baculovirus
• Purity/Purification: > 90% by SDS-PAGE
• Form/Format: Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
• Concentration: 0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
• Sequence: IDETRAHLLL KEKMMRLGGR LVLNTKEELA NERLMTLKIA EMKEAMRTLI FPPSMHFFQA KHLIERSQVF NILRMMPKGA ALHLHDIGIV TMDWLVRNVT YRPHCHICFT PRGIMQFRFA HPTPRPSEKC SKWILLEDYR KRVQNVTEFD DSLLRNFTLV TQHPEVIYTN QNVVWSKFET IFFTISGLIH YAPVFRDYVF RSMQEFYEDN VLYMEIRARL LPVYELSGEH HDEEWSVKTY QEVAQKFVET HPEFIGIKII YSDHRSKDVA VIAESIRMAM GLRIKFPTVV AGFDLVGHED TGHSLHDYKE ALMIPAKDGV KLPYFFHAGE TDWQGTSIDR NILDALMLNT TRIGHGFALS KHPAVRTYSW KKDIPIEVCP ISNQVLKLVS DLRNHPVATL MATGHPMVIS SDDPAMFGAK GLSYDFYEVF MGIGGMKADL RTLKQLAMNS IKYSTLLESE KNTFMEIWKK RWDKFIADVA TKLEHHHHHH
• Sequence Length: 511

• Applicable Applications for CECR1 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for CECR1 recombinant protein

CECR1, also known as adenosine deaminase CECR1 isoform, is a member of a family of adenosine deaminase-related growth factors. Adenosine deaminase is one of the key enzymes of purine nucleotide metabolism. CECR1 is a secreted protein that is expressed in many tissues, with the highest expression in lymphoblasts, heart, lung, and placenta. Recombinant human CECR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Categories/Family for CECR1 recombinant protein

Signal Transduction; Enzymes & Proteases

References

Zavialov AV., et al. (2005) Biochem J. 391:51-57.; Riazi MA., et al. (2000) Genomics. 64:277-285.

NCBI and Uniprot Product Information

• NCBI GI #: 532691754
• NCBI GeneID: 51816
• NCBI Accession #: NP_001269154
• NCBI GenBank Nucleotide #: NM_001282225.1
• UniProt Accession #: Q9NZK5; Q6ICF1; Q86UB6; Q8NCJ2; Q96K41; A8K9H4
• Molecular Weight: 56.9kDa (490aa) 50-70KDa (SDS-PAGE under reducing conditions.)
• NCBI Official Full Name: adenosine deaminase 2 isoform a
• NCBI Official Synonym Full Names: adenosine deaminase 2
• NCBI Official Symbol: ADA2
• NCBI Official Synonym Symbols: PAN; ADGF; CECR1; IDGFL; SNEDS
• NCBI Protein Information: adenosine deaminase 2; adenosine deaminase CECR1
• UniProt Protein Name: Adenosine deaminase 2
• Protein Family: Adenosine deaminase
• UniProt Gene Name: ADA2

NCBI Description

This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.