AminoAcylase-3 Recombinant Protein | ACY3 recombinant protein
Recombinant Human AminoAcylase-3
Gene Names
ACY3; ACY-3; HCBP1
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
AminoAcylase-3; Recombinant Human AminoAcylase-3; ACY3 Human; AminoAcylase-3 Human Recombinant; Aspartoacylase-2; Acylase III; Aminoacylase-3; ACY-3; Hepatitis C virus core-binding protein 1; HCBP1; ACY3; ASPA2; ACY3 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
ACY3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMCSLPVP REPLRRVAVT GGTHGNEMSG VYLARHWLHA PAELQRASFS AVPVLANPAA TSGCRRYVDHDLNRTFTSSF LNSRPTPDDP YEVTRARELN QLLGPKASGQ AFDFVLDLHN TTANMGTCLI AKSSHEVFAM HLCRHLQLQY PELSCQVFLY QRSGEESYNL DSVAKNGLGL ELGPQPQGVL RADIFSRMRT LVATVLDFIE LFNQGTAFPA FEMEAYRPVG VVDFPRTEAG HLAGTVHPQL QDRDFQPLQP GAPIFQMFSG EDLLYEGEST VYPVFINEAA YYEKGVAFVQ TEKFTFTVPA MPALTPAPSP AS
Sequence Length
319
Related Product Information for ACY3 recombinant protein
Description: ACY3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 342 amino acids (1-319 a.a.) and having a molecular mass of 37.6kDa.ACY3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Aspartoacylase 3 (ACY3) belongs to the Aspartoacylase subfamily. ACY3 has a vital role in deacetylating mercapturic acids in kidney proximal tubules. Aspartoacylase 3 localizes to the cytoplasm of S2 and S3 proximal tubules and also to the apical domain of S1 proximal tubules. In addition, ACY3 protein is expressed at low levels in the stomach, testis, heart, brain, lung and liver, and can function as an HCV (Hepatitis C virus) core binding protein.
Introduction: Aspartoacylase 3 (ACY3) belongs to the Aspartoacylase subfamily. ACY3 has a vital role in deacetylating mercapturic acids in kidney proximal tubules. Aspartoacylase 3 localizes to the cytoplasm of S2 and S3 proximal tubules and also to the apical domain of S1 proximal tubules. In addition, ACY3 protein is expressed at low levels in the stomach, testis, heart, brain, lung and liver, and can function as an HCV (Hepatitis C virus) core binding protein.
Product Categories/Family for ACY3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,241 Da
NCBI Official Full Name
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
NCBI Official Synonym Full Names
aspartoacylase (aminocyclase) 3
NCBI Official Symbol
ACY3
NCBI Official Synonym Symbols
ACY-3; HCBP1
NCBI Protein Information
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); HCV core-binding protein 1; acylase III; aminoacylase-3; aspartoacylase-2; hepatitis C virus core-binding protein 1
UniProt Protein Name
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
Protein Family
UniProt Gene Name
ACY3
UniProt Synonym Gene Names
ASPA2; ACY-3; HCBP1; HCV core-binding protein 1
UniProt Entry Name
ACY3_HUMAN
Uniprot Description
ACY3: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein type: Hydrolase; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 3.5.1.114; Amino Acid Metabolism - histidine
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: apical plasma membrane; cytosol
Molecular Function: identical protein binding; metal ion binding; hydrolase activity, acting on ester bonds; aminoacylase activity
Biological Process: viral reproduction; xenobiotic metabolic process
Research Articles on ACY3
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Product Notes
The ACY3 acy3 (Catalog #AAA145406) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMCS LPVP REPLRRVAVT GGTHGNEMSG VYLARHWLHA PAELQRASFS AVPVLANPAA TSGCRRYVDH DLNRTFTSSF LNSRPTPDDP YEVTRARELN QLLGPKASGQ AFDFVLDLHN TTANMGTCLI AKSSHEVFAM HLCRHLQLQY PELSCQVFLY QRSGEESYNL DSVAKNGLGL ELGPQPQGVL RADIFSRMRT LVATVLDFIE LFNQGTAFPA FEMEAYRPVG VVDFPRTEAG HLAGTVHPQL QDRDFQPLQP GAPIFQMFSG EDLLYEGEST VYPVFINEAA YYEKGVAFVQ TEKFTFTVPA MPALTPAPSP AS. It is sometimes possible for the material contained within the vial of "AminoAcylase-3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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