Serine/threonine-protein kinase receptor R3 (Acvrl1) Recombinant Protein | Acvrl1 recombinant protein
Recombinant Rat Serine/threonine-protein kinase receptor R3 (Acvrl1)
NCBI and Uniprot Product Information
NCBI Description
may play a role in TGF-beta mediated transmembrane signaling in blood vessels [RGD, Feb 2006]
Uniprot Description
ALK1: a kinase of the STKR family. A type I cell-surface receptor for the TGF-beta superfamily of ligands including Activin A. Highly expressed in human placenta and lung. Deficiency causes hemorrhagic telangiectasia type 2 also known as Rendu-Osler-Weber syndrome 2.
Protein type: Protein kinase, TKL; Kinase, protein; Membrane protein, integral; EC 2.7.11.30; Protein kinase, Ser/Thr (receptor); TKL group; STKR family; Type1 subfamily
Cellular Component: cell surface; cell soma; integral to plasma membrane; dendrite
Molecular Function: transforming growth factor beta receptor activity; protein serine/threonine kinase activity; activin receptor activity, type I; transforming growth factor beta receptor activity, type I; transforming growth factor beta binding; metal ion binding; activin binding; SMAD binding; protein kinase binding; ATP binding; transmembrane receptor protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity
Biological Process: blood circulation; protein heterooligomerization; positive regulation of transcription, DNA-dependent; activin receptor signaling pathway; negative regulation of cell adhesion; signal transduction; protein amino acid phosphorylation; BMP signaling pathway; negative regulation of cell proliferation; positive regulation of endothelial cell differentiation; negative regulation of endothelial cell differentiation; regulation of transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; regulation of blood pressure; lymphangiogenesis; angiogenesis; negative regulation of cell migration; positive regulation of BMP signaling pathway; in utero embryonic development; negative regulation of focal adhesion formation; negative regulation of blood vessel endothelial cell migration; positive regulation of angiogenesis; negative regulation of endothelial cell proliferation; blood vessel morphogenesis; positive regulation of transcription from RNA polymerase II promoter; blood vessel remodeling; positive regulation of endothelial cell proliferation; negative regulation of cell growth; wound healing, spreading of epidermal cells
Research Articles on Acvrl1
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Product Notes
The Acvrl1 acvrl1 (Catalog #AAA961682) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-121. The amino acid sequence is listed below: KGDLVKPSRG QLVNCTCENP HCKRPICQGA WCTVVLVREQ GRHPQVYRGC GSLNQELCLG RPTEFVNHHC CYRSFCNHNV SLMLEATQTP SEEPEVDAHL P. It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase receptor R3 (Acvrl1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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