TRAP 5 Active Protein
TRAP 5, Recombinant, Human (Tartrate-resistant Acid Phosphatase Serum band 5, TRAcP 5, ACP5, PAP, EC 3.1.3.2)
Purity
Highly Purified95%, as determined by SDS-PAGE and visualized by silver stain.
Synonyms
TRAP 5; Recombinant; Human (Tartrate-resistant Acid Phosphatase Serum band 5; TRAcP 5; ACP5; PAP; EC 3.1.3.2); TRAP 5 active protein
Purity/Purification
Highly Purified
95%, as determined by SDS-PAGE and visualized by silver stain.
95%, as determined by SDS-PAGE and visualized by silver stain.
Form/Format
Supplied as a liquid in 25mM Tris, 0.15M sodium chloride, pH 7.5.
Activity
65,000pmoles/min/ug. Measured by its ability to cleave a substrate, p-Nitrophenyl phosphate (pNPP).
Endotoxin Level
< 1EU/ug (LAL)
Preparation and Storage
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for TRAP 5 active protein
Encoded by the ACP5 gene, Tartrate Resistant Acid Phosphatase (TRACP or TRAP) is also known as Purple Acid Phosphatase (PAP) or Acid Phosphatase 5 (ACP5) (1). The deuced amino acid sequence of human ACP5 (Accession # NP_001602) predicts a signal peptide (aa 1 to 21) and a mature chain (aa 22 to 325). rhACP5 consists of aa 22 to 320, without the last 5 residues, RRARP. ACP5 is expressed at high levels by osteoclasts, macrophages and dendritic cells (2). Two forms, 5a and 5b, circulating in human blood, are derived from different cell types and have different functions. Derived from macrophages and dendritic cells, 5a is a marker of inflammatory conditions. Derived from osteoclasts, 5b is a marker of bone resorption. Compared to 5a, 5b does not contain sialic acid residues, has a higher specific activity and pH optimum, and may be processed into a disulfide-linked dimer (3).
Product Categories/Family for TRAP 5 active protein
NCBI and Uniprot Product Information
Similar Products
Product Notes
The TRAP 5 (Catalog #AAA637590) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TRAP 5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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