Hepcidin / LEAP-1 Active Peptide
Hepcidin / LEAP-1
Synonyms
Hepcidin / LEAP-1; Hepcidin / LEAP-1 active peptide
Solution
Do not remove the cap. Inject 390 ,.11 of distilled water into the vial using a calibrated syringe.
Dissolve all the contents thoroughly.
This procedure furnishes a 0.1 mM solution of the titled compound.
Dissolve all the contents thoroughly.
This procedure furnishes a 0.1 mM solution of the titled compound.
Structure
Asp-Thr-His-Phe-Pro-lle-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-ArgSer-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr
(Reported disulfide bonds between Cys7-Cys23, Cys10-CYS13, Cys11-Cys19, and Cys14-Cys22)
(Reported disulfide bonds between Cys7-Cys23, Cys10-CYS13, Cys11-Cys19, and Cys14-Cys22)
Molecular Structure
C113H170N34O31S9
Preparation and Storage
Storage(solution): After preparing 100-200 ul aliquots, freeze them at -20°C or below until use. The aqueous solution should be used within a few weeks.
Storage (powder): The undissolved compound should be stored below -20°C.
Storage (powder): The undissolved compound should be stored below -20°C.
Related Product Information for Hepcidin / LEAP-1 active peptide
Hepcidin / LEAP-1 (Human) Liver-Expressed Antimicrobial Peptide 1 (Human) Hepcidin-25 Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr (Disulfide bonds between Cys7- Cys23, Cys10-Cys13, Cys11- Cys19, and Cys14-Cys22 [reference 5 below]) (M.W. 2789.4) C113H170N34O31S9 Liver-Specific Antimicrobial Peptide / Iron-Regulatory Hormone (Regulation of Iron Homeostasis) 1. A. Krause, S. Neitz, H.-J. Mägert, A. Schulz, W.-G. Forssmann, P. Schulz-Knappe, and K. Adermann,FEBS Lett.,480,147 (2000).(Original; LEAP-1) 2. C.H. Park, E.V. Valore, A.J. Waring, and T. Ganz,J. Biol. Chem.,276,7806 (2001).(Original; Hepcidin) 3. T. Ganz and E. Nemeth, Am. J. Physiol., 290, G199 (2006). (Review) 4. H.N. Hunter, D.B. Fulton, T. Ganz, and H.J. Vogel, J. Bio Chem., 277, 37597 (2007). (Previously Published S-S Bond Connectivity) 5. J. B. Jordan, L. Poppe, M. Haniu, T. Arvedson, R. Syed, V. Li, H. Kohno, H. Kim, P. D. Schnier, T. S. Harvey, L. P. Miranda, J. Cheetham, and B. J. Sasu,J. Biol. Chem., 284, 24155 (2009).(Hepcidin S-S Bond)
Product Categories/Family for Hepcidin / LEAP-1 active peptide
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Product Notes
The Hepcidin / LEAP-1 (Catalog #AAA405734) is an Active Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Hepcidin / LEAP-1, Active Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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