SDS-PAGE
3-ketoacyl-CoA thiolase Recombinant Protein | ACAA2 recombinant protein
Recombinant Human 3-ketoacyl-CoA thiolase, mitochondrial
Gene Names
ACAA2; DSAEC
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
3-ketoacyl-CoA thiolase; Recombinant Human 3-ketoacyl-CoA thiolase; mitochondrial; Acetyl-CoA acyltrans ferase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; ACAA2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
17-397aa; Full Length
Sequence
FGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
Sequence Length
397
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for ACAA2 recombinant protein
Abolishes BNIP3-mediated apoptosis and mitochondrial damage.
Product Categories/Family for ACAA2 recombinant protein
References
Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase.Abe H., Ohtake A., Yamamoto S., Satoh Y., Takayanagi M., Amaya Y., Takiguchi M., Sakuraba H., Suzuki Y., Mori M., Niimi H.Biochim. Biophys. Acta 1216:304-306(1993)
Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF)
at the surface of caveolae in human adipocytes.Aboulaich N., Vainonen J.P., Stralfors P., Vener A.V.Biochem. J. 383:237-248(2004)
Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines.Cao W., Liu N., Tang S., Bao L., Shen L., Yuan H., Zhao X., Lu H.Biochim. Biophys. Acta 1780:873-880(2008)
A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008)
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011)
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42.2 kDa
NCBI Official Full Name
3-ketoacyl-CoA thiolase, mitochondrial
NCBI Official Synonym Full Names
acetyl-CoA acyltransferase 2
NCBI Official Symbol
ACAA2
NCBI Official Synonym Symbols
DSAEC
NCBI Protein Information
3-ketoacyl-CoA thiolase, mitochondrial
UniProt Protein Name
3-ketoacyl-CoA thiolase, mitochondrial
Protein Family
UniProt Gene Name
ACAA2
UniProt Entry Name
THIM_HUMAN
NCBI Description
The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]
Uniprot Description
ACAA2: Abolishes BNIP3-mediated apoptosis and mitochondrial damage. Belongs to the thiolase family.
Protein type: Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.16; Transferase
Chromosomal Location of Human Ortholog: 18q21.1
Cellular Component: mitochondrial inner membrane; mitochondrion
Molecular Function: acetyl-CoA C-acyltransferase activity; protein binding
Biological Process: cholesterol biosynthetic process; fatty acid metabolic process
Research Articles on ACAA2
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Product Notes
The ACAA2 acaa2 (Catalog #AAA950688) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 17-397aa; Full Length. The amino acid sequence is listed below: FGAYGGLLKD FTATDLSEFA AKAALSAGKV SPETVDSVIM GNVLQSSSDA IYLARHVGLR VGIPKETPAL TINRLCGSGF QSIVNGCQEI CVKEAEVVLC GGTESMSQAP YCVRNVRFGT KLGSDIKLED SLWVSLTDQH VQLPMAMTAE NLAVKHKISR EECDKYALQS QQRWKAANDA GYFNDEMAPI EVKTKKGKQT MQVDEHARPQ TTLEQLQKLP PVFKKDGTVT AGNASGVADG AGAVIIASED AVKKHNFTPL ARIVGYFVSG CDPSIMGIGP VPAISGALKK AGLSLKDMDL VEVNEAFAPQ YLAVERSLDL DISKTNVNGG AIALGHPLGG SGSRITAHLV HELRRRGGKY AVGSACIGGG QGIAVIIQST A. It is sometimes possible for the material contained within the vial of "3-ketoacyl-CoA thiolase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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